Giancarlo Castaman Selected Research

Type 1 von Willebrand Disease

12/2020	How I treat von Willebrand disease.
5/2013	Principles of care for the diagnosis and treatment of von Willebrand disease.
3/2013	VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease.
4/2011	Bleeding tendency and efficacy of anti-haemorrhagic treatments in patients with type 1 von Willebrand disease and increased von Willebrand factor clearance.
11/2010	The impact of bleeding history, von Willebrand factor and PFA-100(®) on the diagnosis of type 1 von Willebrand disease: results from the European study MCMDM-1VWD.
5/2008	Identification of type 1 von Willebrand disease patients with reduced von Willebrand factor survival by assay of the VWF propeptide in the European study: molecular and clinical markers for the diagnosis and management of type 1 VWD (MCMDM-1VWD).
4/2008	Evidence-based diagnosis of type 1 von Willebrand disease: a Bayes theorem approach.
4/2008	Response to desmopressin is influenced by the genotype and phenotype in type 1 von Willebrand disease (VWD): results from the European Study MCMDM-1VWD.
1/2007	Phenotype and genotype of a cohort of families historically diagnosed with type 1 von Willebrand disease in the European study, Molecular and Clinical Markers for the Diagnosis and Management of Type 1 von Willebrand Disease (MCMDM-1VWD).

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Giancarlo Castaman Research Topics

Disease

65	Hemorrhage 07/2022 - 01/2003
49	Hemophilia A (Haemophilia) 07/2022 - 07/2007
22	von Willebrand Diseases (von Willebrand's Disease) 08/2022 - 01/2002
12	Hemophilia B (Haemophilia B) 01/2022 - 01/2008
9	Type 1 von Willebrand Disease 12/2020 - 01/2007
7	Thrombosis (Thrombus) 10/2019 - 09/2002
6	Neoplasms (Cancer) 01/2022 - 11/2002
6	Venous Thromboembolism 01/2019 - 09/2002
5	Thrombocytopenia (Thrombopenia) 05/2022 - 04/2008
5	Joint Diseases (Joint Disease) 01/2021 - 02/2016
4	Type 3 von Willebrand Disease 01/2022 - 01/2005
4	Type 2 von Willebrand Disease 01/2020 - 01/2009
4	Thrombophilia 03/2012 - 08/2002
3	Liver Diseases (Liver Disease) 01/2020 - 10/2017
3	Multiple Myeloma 01/2016 - 11/2002
3	Afibrinogenemia (Fibrinogen Deficiency) 07/2015 - 10/2007
3	Vascular System Injuries 09/2013 - 01/2003
3	Inherited Blood Coagulation Disorders 09/2013 - 09/2008
3	Venous Thrombosis (Deep-Vein Thrombosis) 10/2003 - 08/2002
2	Hypersensitivity (Allergy) 07/2022 - 11/2021
2	Infections 01/2022 - 01/2020
2	Hemarthrosis 01/2020 - 02/2016
2	Menorrhagia 01/2020 - 04/2011
2	Hematologic Neoplasms (Hematological Malignancy) 01/2019 - 01/2018
2	Inflammation (Inflammations) 01/2016 - 04/2007
2	Gaucher Disease (Gaucher's Disease) 01/2016 - 05/2015
2	Polycythemia Vera 01/2008 - 09/2002
2	Essential Thrombocythemia 01/2008 - 09/2002
1	Pain (Aches) 07/2022
1	COVID-19 05/2022
1	Factor XIII Deficiency 02/2022
1	Autoimmune Diseases (Autoimmune Disease) 01/2022
1	Pulmonary Arterial Hypertension 01/2022
1	Immune System Diseases (Immune Disorders) 01/2021
1	Metabolic Bone Diseases (Osteopenia) 09/2020
1	Wounds and Injuries (Trauma) 03/2020
1	Epistaxis (Nosebleed) 01/2020

Drug/Important Bio-Agent (IBA)

37	von Willebrand FactorIBA 08/2022 - 01/2002
34	Factor VIII (Coagulation Factor VIII)IBA 08/2022 - 02/2002
11	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2003
11	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 12/2020 - 01/2005
10	Factor IX (Coagulation Factor IX)FDA LinkGeneric 01/2022 - 12/2007
9	Blood Coagulation Factors (Coagulation Factor)IBA 03/2020 - 09/2008
6	Hemostatics (Antihemorrhagics)IBA 01/2021 - 01/2013
5	recombinant FVIIa (rFVIIa)FDA Link 07/2022 - 09/2017
5	AntibodiesIBA 07/2022 - 10/2015
5	Biological ProductsIBA 05/2022 - 04/2008
5	emicizumabIBA 01/2021 - 01/2020
5	AntigensIBA 01/2020 - 04/2003
5	Prothrombin (Factor II)IBA 11/2019 - 07/2004
5	AnticoagulantsIBA 11/2019 - 09/2002
5	Biomarkers (Surrogate Marker)IBA 03/2013 - 01/2007
4	Pharmaceutical PreparationsIBA 09/2018 - 04/2008
4	Factor XI (Plasma Thromboplastin Antecedent)IBA 09/2013 - 12/2007
3	CytokinesIBA 01/2021 - 01/2016
3	Monoclonal AntibodiesIBA 01/2021 - 01/2020
3	Neutralizing AntibodiesIBA 11/2019 - 09/2013
3	Fibrinogen (Factor I)FDA Link 10/2019 - 07/2009
3	Nonsense Codon (Nonsense Mutation)IBA 01/2017 - 09/2012
3	factor V LeidenIBA 10/2013 - 09/2002
3	Protein CIBA 04/2007 - 08/2002
3	Factor V (Coagulation Factor V)IBA 02/2004 - 09/2002
2	Factor VII (Proconvertin)IBA 07/2022 - 11/2021
2	BESIBA 07/2022 - 01/2022
2	concizumabIBA 01/2022 - 11/2019
2	Platelet Glycoprotein GPIb-IX Complex (Glycoprotein Ib)IBA 10/2020 - 01/2009
2	RistocetinIBA 01/2020 - 07/2016
2	Thrombin FDA Link 11/2019 - 01/2019
2	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 01/2019 - 03/2012
2	Factor VIIa (Activated Factor VII)IBA 09/2018 - 09/2017
2	Glucosylceramides (Glucocerebrosides)IBA 01/2016 - 05/2015
2	EnzymesIBA 01/2016 - 05/2015
2	Glucosylceramidase (Glucocerebrosidase)IBA 01/2016 - 05/2015
2	von Willebrand factor drug combination factor VIIIIBA 06/2010 - 07/2007
1	Amino Acids FDA Link 05/2022
1	recombinant factor XIII-A2IBA 02/2022
1	Asialoglycoprotein ReceptorIBA 01/2022
1	AutoantibodiesIBA 01/2022
1	BAY 94-9027IBA 01/2021
1	6-pyruvoyltetrahydropterin synthase (PTPS)IBA 01/2021
1	IsoantibodiesIBA 01/2021
1	Factor VIIIaIBA 01/2021
1	B-Cell Activating FactorIBA 01/2021
1	25-hydroxyvitamin DIBA 09/2020
1	OsteocalcinIBA 09/2020
1	hydroxide ionIBA 09/2020
1	Alkaline PhosphataseIBA 09/2020
1	Parathyroid Hormone (Parathormone)IBA 09/2020
1	Collagen Type I (Type I Collagen)IBA 09/2020
1	Hyaluronic Acid (Hyaluronan)IBA 07/2020
1	Antiviral Agents (Antivirals)IBA 01/2020

Therapy/Procedure

21	Therapeutics 01/2022 - 07/2007
2	Platelet Transfusion (Blood Platelet Transfusions) 01/2018 - 11/2016
2	Drug Therapy (Chemotherapy) 01/2018 - 11/2016
2	Operative Surgical Procedures 02/2016 - 01/2008
2	Contraindications 07/2007 - 01/2005
1	Perioperative Care 11/2021
1	Arthroplasty 01/2021
1	Replacement Arthroplasty 01/2021
1	Viscosupplementation 07/2020